Researchers discover that Sleep and ageing are two sides of one coin?
on 26 March 2019
Hypnotic power naps

If you are constantly feeling tired, not getting enough sleep or just feel like you have way too much on your mind to get a good nights sleep, then be warned, you are putting yourself at great harm, maybe not now but for sure at some point in the future. To prevent that, why not try a hypnotic power nap. . . . 

The dichotomy of sleep!

As far as the brain is concerned, sleep is a very complex and complicated process and one in which a very large part of our brain is involved in monitoring. From an evolutionary perspective, sleep puts an animal at great risk and exposure to its predators. In that context, it's not much different these days, although the predators are merely different. In the past it was a tiger or a bear or maybe an invader from another tribe, these days, it's your mortgage payment, the promotion you were hoping for, or a partners health, maybe your own etc. Of course in modern life, these things can play out in dreams. nightmares, or disrupted sleep?  

Since stress, in its many forms impairs the way our brain works, which is often a cause of much sleep disturbance, it becomes imperative that you learn to improve both the quality and duration of your sleep. The recommended period being 7 to 8 hours per day. During sleep, our brain rhythms slow down, from beta to alpha to theta and then delta brainwaves. Theta is now categorized as REM (rapid eye movement), and NonREM 1, 2, 3, Of those REM and NonRem 2 are the waves where dreaming occurs, as well as some repair, although NonREM 3 is where most of the brain's reparative function occurs. So, given that, it becomes easier to understand that the lesser or the poorer the sleep, the lesser or the poorer the repair that can take place!

To help you overcome poor sleep or insomnia, I would highly recommend hypnotherapy and hypnotic power naps. Using hypnosis, it is possible to go into a very deep state and very quickly too. A 40-minute hypnotic power nap is roughly the equivalent of a few hours of ordinary sleep because you go very deep, very quickly and stay there for most of that time; Hypnosis, you know it makes sense!

Hypnotherapy stands out as one of the most effective strategic life management methods there is, especially in its ability to promote clear thinking and good states of mental wellness. The behaviours that make life challenging are often a result of too much stress, too little sleep and too little by way of clarity! So, to get or take back control of your mind and your life, it makes perfect sense to use a methodology that addresses the subconscious mind's role in perpetuating negative, vague and ambiguous states of mind. Hypnosis helps us to create calm relaxing states of mind that make life work better! If you would like to address any concerns you have in this direction, or, if you just want to make your life feel better,  then why not make an appointment for a Free Consultation? Hypnosis gives you the ability to have a good life! 

The objective here is to help people understand how and why we become illogically trapped into irrational emotional experiences that may actually be happening for reasons different to that which we would imagine! If you want to know more about how Hypnotherapy can help you; why not make an appointment for a Free Consultation?

For more information on the Free Consultation - Go Here or to book your Free Consultation today, you can do so here

The Research:

Oxford University researchers have discovered a brain process common to sleep and ageing in research that could pave the way for new treatments for insomnia.

Writing in the journal Nature, the scientists report how oxidative stress leads to sleep. Oxidative stress is also believed to be a reason why we age and a cause of degenerative diseases.

The researchers say the discovery brings us closer to understanding the still-mysterious function of sleep and offers new hope for the treatment of sleep disorders. It may also explain why, as is suspected, chronic lack of sleep shortens life.

Professor Gero Miesenböck, Director of Oxford University's Centre for Neural Circuits and Behaviour, who led the Oxford team, said: 'It's no accident that oxygen tanks carry explosion hazard labels: uncontrolled combustion is dangerous. Animals, including humans, face a similar risk when they use the oxygen they breathe to convert food into energy: imperfectly contained combustion leads to "oxidative stress" in the cell. This is believed to be a cause of ageing and a culprit for the degenerative diseases that blight our later years. Our new research shows that oxidative stress also activates the neurons that control whether we go to sleep.'

The team studied the regulation of sleep in fruit flies -- the animal that also provided the first insight into the circadian clock nearly 50 years ago. Each fly has a special set of sleep-control neurons, brain cells that are also found in other animals and believed to exist in people. In previous research [Nature 2016; 536: 333-337], Professor Miesenböck's team discovered that these sleep-control neurons act like an on-off switch: if the neurons are electrically active, the fly is asleep; when they are silent, the fly is awake.

Dr Seoho Song, a former graduate student in the Miesenböck lab and one of the two lead authors of the study, said: 'We decided to look for the signals that switch the sleep-control neurons on. We knew from our earlier work that the main difference between sleep and waking is how much electrical current flows through two ion channels, called Shaker and Sandman. During sleep, most of the current go through Shaker.'

Ion channels generate and control the electrical impulses through which brain cells communicate.

'This turned the big, intractable question "Why do we sleep?" into a concrete, solvable problem,' said Dr Song. 'What causes the electrical current to flow through Shaker?'

The team found the answer in a component of the Shaker channel itself.

Lead author and postdoctoral fellow in the Miesenböck group, Dr Anissa Kempf, explained: 'Suspended underneath the electrically conducting portion of Shaker is another part, like the gondola under a hot air balloon. A passenger in the gondola, the small molecule NADPH, flips back and forth between two chemical states -- this regulates the Shaker current. The state of NADPH, in turn, reflects the degree of oxidative stress the cell has experienced. Sleeplessness causes oxidative stress, and this drives the chemical conversion.'

In a striking demonstration of this mechanism, a flash of light that flipped the chemical state of NADPH put flies to sleep.

According to Professor Miesenböck, drugs that change the chemistry of Shaker-bound NADPH, in the same way, could be a powerful new type of sleeping pill.

'Sleep disturbances are very common,' he said, 'and sleeping pills are among the most commonly prescribed drugs. But existing medications carry risks of confusion, forgetfulness and addiction. Targeting the mechanism we have discovered could avoid some of these side effects.'

Story Source:

Materials provided by the University of OxfordNote: Content may be edited for style and length.

Journal Reference:

  1. Anissa Kempf, Seoho M. Song, Clifford B. Talbot, Gero Miesenböck. A potassium channel β-subunit couples mitochondrial electron transport to sleepNature, 2019; DOI: 10.1038/s41586-019-1034-5

Cite This Page:

The University of Oxford. "Sleep and ageing: Two sides of one coin?." ScienceDaily. ScienceDaily, 21 March 2019. <>.