Prince Charming's kiss unlocking brain's regenerative potential?

on 07 July 2019
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The answer to life's ripples

 Day by day science expands the envelope of brain research, so they are definitely moving in the right direction. So, hopefully, in the not too distant future, we'll get hooked up to brain analyzer, much the same way your car is when in for a tune up and come out in tip-top condition. Until then, I suggest you rely on a more traditional form of mental tune up, hyp[notherapy . . . 

 Life in one way or another is a consequence of how our genes express themselves, 

Hypnotherapy really does have an exciting ability to heal and it does that by helping you to realign old memories (memory reconsolidation) or it can help build new ones (memory consolidation), these processes begin to happen during the period of hypnotic treatment and this is later consolidated (stabilised) when the brain is in specific brainwave states when we sleep at nighttime. Hypnosis basically mimics this natural process because the states that occur during hypnosis are akin to the process of sleeping. We know that state as the nebulous world of hypnotic trance!

Most of the neural stem cells, relating to hypnotherapy, are from the subgranular zone of the dentate gyrus, part of the hippocampal formation. Distress (stress) both psychological and oxidative affect the number and quality of these stem cells. This has an ongoing effect on the way we record, store and recall memory. Essentially distress has a huge impact on the quality of our lives and hypnotherapy is here to help you, until such times that scientists discover safer and more effective ways to provide neurological interventions.

Hypnotherapy stands out as one of the most effective strategic life management methods there is, especially in its ability to promote clear thinking and good states of mental wellness. The behaviours that make life challenging are often a result of too much stress, too little sleep and too little by way of clarity! So, to get or take back control of your mind and your life, it makes perfect sense to use a methodology that addresses the subconscious mind's role in perpetuating negative, vague and ambiguous states of mind. Hypnosis helps us to create calm relaxing states of mind that make life work better! If you would like to address any concerns you have in this direction, or, if you just want to make your life feel better, then why not make an appointment for a Free Consultation? Hypnosis gives you the ability to have a good life! 

The objective here is to help people understand how and why we become illogically trapped into irrational emotional experiences that may actually be happening for reasons different to that which we would imagine! If you want to know more about how Hypnotherapy can help you; why not make an appointment for a Free Consultation?

For more information on the Free Consultation - Go Here or to book your Free Consultation today, you can do so here

The Research:

The human body has powerful healing abilities. But treating brain disorders is no easy task, as brain cells -- neurons -- have limited ability to regenerate. Nonetheless, stem cells are a form of natural backup, a vestige of our days as still-developing embryos.

The difficulty is that, as we age, our brains' stem cells 'fall asleep' and become harder to wake up when repairs are needed. Despite efforts to harness these cells to treat neurological damage, scientists have until recently been unsuccessful in decoding the underlying 'sleep' mechanism.

Now, researchers at Kyoto University studying brain chemistry in mice have revealed the ebb and flow of gene expression that may wake neural stem cells from their slumber. These findings, which may also apply to stem cells elsewhere in the body, were recently published in the journal Genes & Development.

"No one before us has directly compared active stem cells in embryos with inactive, 'quiescent' adult stem cells," says group leader Ryoichiro Kageyama of Kyoto University's Institute for Frontier Life and Medical Sciences, who points out that at least two genes and their associated proteins regulating activation had already been identified.

The team focused their attention on protein 'Hes1', which is strongly expressed in the adult cells. This normally suppresses the production of other proteins such as 'Ascl1', small amounts of which are periodically produced by active stem cells.

Monitoring the production of the two proteins over time, the team pinpointed a wave-like pattern that leads to stem cells waking up and turning into neurons in the brain.

When they 'knocked out' the genetic code needed to make Hes1, the cells started to make more Ascl1, which then activated almost all the neural stem cells.

"It is key that the same genes are responsible for both the active and quiescent states of these stem cells," Kageyama adds. "Only the expression dynamics differ between the two."

"A better understanding of the regulatory mechanisms of these different expression dynamics could allow us to switch the dormant cells on as part of a treatment for a range of neurological disorders."

Story Source:

Materials provided by Kyoto UniversityNote: Content may be edited for style and length.

Journal Reference:

  1. Risa Sueda, Itaru Imayoshi, Yukiko Harima, Ryoichiro Kageyama. High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brainGenes & Development, 2019; 33 (9-10): 511 DOI: 10.1101/gad.323196.118

Cite This Page:

Kyoto University. "Prince Charming's kiss unlocking the brain's regenerative potential? Kyoto University identifies 'wake-up' signal for deep-sleeping neural stem cells." ScienceDaily. ScienceDaily, 10 May 2019. <>.